Exome Screening
Book an AppointmentExome Screening
Exome screening is used to diagnose for unidentified hereditary diseases or polygenic
diseases; that usually involve two or more genes interacting. In this screening process,
regions of tens of thousands of genes are analyzed at the same time to gather results
indicating the presence of an unknown hereditary disease.
Who is the right candidate for exome screening?
Exome screening is recommended to couples who expect that either one of them carries an
unidentified genetic disease or polygenic disease. Therefore, the right candidate for exome
screening is:
- Either spouse in a couple with an unknown history of hereditary disease
- Couples who once had a genetically abnormal child
- Couples with close relatives having an unknown history of genetic disease
Seeds of innocence expertise
Our team of specialists will initiate the process of screening by accessing your health &
medical history, followed by deciding the course of action for conducting exome screening.
FAQ’s
Q. How accurate is whole-exome sequencing?
It is not possible to capture & sequence 100% of the exome at high quality. On average, more than 99.4% of the exome sequence is captured to provide reliable variant calls. In rare and ultra-rare cases, exome screening can provide a diagnosis of up to 50% of the cases.
Q. Is Next Generation Sequencing the same as whole-genome sequencing?
No, these two are not the same. Next-generation sequencing is a type of sequencing technology. It essentially means all of the post-Sanger sequencing technologies. On the other hand, Whole-genome sequencing” is a sequencing application. It essentially means sequencing the entire genome of an organism.
Q. What can whole genome sequencing reveal?
Whole-genome sequencing can reveal information related to the DNA of an individual, but, also probable DNA sequence of close genetic relatives.
Q. What is a clinical exome?
The Clinical Exome analysis is used to investigate any complex health and developmental
problem that is suspected of having a genetic cause. This testing is commonly used when
other analysis fails to determine the cause of health problems.
Our Doctors
Dr. Gauri Agarwal
Infertility Specialist
Dr. Gauri Agarwal is a young, dynamic and leading fertility specialist of Delhi/NCR. Dr. Agarwal is backed by a visionary thinking, die-hard determination and industry-rich experience of more than 10 years. She is the Director, IVF at Seeds of Innocence Centre. Dr. Agarwal finished her MBBS degree from Bharati Vidyapeeth Medical College, Pune. Post that, she did a Diplomate of National Board (DNB), Obstetrics and Gynaecology Residency Program from KG Superspecialty Hospital, Coimbatore. She followed this with a hard-earned Fellowship Program in Reproductive Medicine (Infertility) from the University of Gent, Belgium. Further, she received training in Embryology at the National University of Singapore.
Dr. Gazala Shahnaz
Senior Consultant Fetal Medicine
Dr. Gazala is young & dynamic maternal fetal medicine specialist with keen interest in prenatal screening and diagnosis, and Medical disorders with pregnancy, multiple pregnancy and Fetal growth restriction. She completed her post-graduation in Obstetrics & Gynaecology from the northern railway central hospital, New Delhi followed by fellowship in maternal & Fetal Medicine from prestigious Maulana Azad Medical College new Delhi. She is Fetal Medicine Foundation (FMF UK) certified in 11–13+6 weeks scan, anomaly scan, dopplers in obstetrics , cervical assessment and fetal interventions. She has multiple publications in journals of national and international Journal. She is also reviewer on British medical Journal(BMJ). She is certified by the Fetal Medicine Foundation (FMF, UK) to perform the 11-13+6 weeks’ scan, obstetric Dopplers, cervical screening. She is currently working as Fetal Medicine Consultant, at Seeds of innocence, Malviya Nagar.
Dr. Vandana Mishra
Infertility Specialist
Dr. Vandana Mishra has completed her MBBS from the prestigious Lady Hardinge Medical College, University of Delhi and has received her Masters in Obstetrics & Gynecology from the prestigious University College of Medical Sciences, New Delhi. She received gold medal in her masters degree. She has pursued her interest in the field of Assisted Reproductive Medicine, through a comprehensive Fellowship Course in Infertility & Reproductive Medicine from Nova IVI Spain/India. She is trained in pelvic ultrasounds, ovulation induction, IUI, IVF / ICSI, laparoscopy and hysteroscopy. She has a vast experience in handling difficult infertility cases including PCOS, Endometriosis, low egg reserve and azoospermia. Her special interest is dealing patients with recurrent pregnancy losses and genetic abnormalities. She has been successfully heading the Seeds of Innocence fertility centre at Patna since 2019 with utmost diligence yielding excellent success rates and patient satisfaction.
Dr. Julie Chhawchharia
Infertility Specialist
Dr. Julie Chhawchharia, is a competent and committed Infertility specialist in Reproductive Medicine with around a decade of extensive experience along with experience in obstetrics and gynaecology. She has been performing vaginal deliveries, caesarean sections, and various gynaecological surgeries.. She is an acknowledged expert in Reproductive Medicine services by DY Patil University, Navi Mumbai. She is also a meritorious and Gold award-winning student of Fellowship and Diploma in Minimal Access Surgery (Laparoscopy) from the prestigious World Laparoscopy Hospital, Gurgaon in 2014. She completed her MBBS degree and MS in Obstetrics and Gynaecology from the renowned Institute JJM Medical College in Davangere, Karnataka.
Dr. Shruti Singh
Infertility Specialist
Dr Shruti Singh is Senior Infertility Consultant and Centre Head at Seeds of innocence IVF centre, Ranchi. She has more than a decade of experience in the field of Gynaecology and Infertility. She has specialised in the areas of IVF, IUI, ICSI, TESA, TESE, Reproductive medicine, embryo transfer, cryopreservation, gynaecological endoscopic surgeries and other fertility related procedures from one of the India’s leading Fertility Academy. She is passionate about utmost patient care and is determined to give best of IVF results with latest technologies in the most economical scenario. She has been doing around 30-40 IVF cycles per month with a consistent result of 70-80% . She has done her MBBS, MS (OBGY) from MUHS, Nashik and has trained herself in endoscopic procedures under Dr Pradeep Garg (AIIMS, New Delhi). She is trained at FOGSI recognised ultrasound training centre in the field of basic and advanced gynaecological and obstetrics ultrasonography from Mumbai. She has bagged around 17 publications in National and International Journals and has experience of paper presentations at various national conferences.
Dr. Seema Madan
Infertility Specialist
Dr. Seema has done her M.D (Obstetrics & gynecology) from Maharshi Dayanand University, Rohtak Haryana. She has 19 year experience in Gynecology. Before joining Seeds of Innocence she was at ART at KJIVF and Laparoscopy Center as Consultant. She also worked at Fortis Bloom IVF, lady Harding Medical College, and Fortis Escorts Hospital & Research Centre.